49ers vs Chargers Score and Box Score | ChirpSan Francisco 49ers vs Los Angeles Chargers score
| Passing | C/ATT | YDS | AVG | TD | INT | SACKS | RTG |
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| Mac Jones | 6/13 | 89 | 6.8 | 0 | 0 | 0-0 | 69.1 |
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| Adrian Martinez | 8/17 | 57 | 3.4 | 1 | 2 | 0-0 | 35.3 |
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| Brock Purdy |
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| Rushing | CAR | YDS | AVG | TD | LONG |
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| Sincere McCormick | 6 | 53 | 8.8 | 1 | 37 |
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| Kaelon Black | 8 | 33 | 4.1 | 0 | 9 |
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| Zamir White | 12 | 29 | 2.4 | 0 | 9 |
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| Khalil Herbert | 4 | 17 | 4.3 | 1 | 10 |
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| Adrian Martinez | 4 | 10 | 2.5 | 1 | 9 |
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| Brock Purdy | 1 | 3 | 3.0 | 0 | 3 |
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| Mac Jones | 1 | 1 | 1.0 | 0 | 1 |
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| Receiving | REC | YDS | AVG | TD | LONG | TGTS |
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| KhaDarel Hodge | 4 | 46 | 11.5 | 0 | 20 | 4 |
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| De'Zhaun Stribling | 4 | 46 | 11.5 | 0 | 21 | 5 |
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| Jordan Watkins | 3 | 41 | 13.7 | 1 | 24 | 4 |
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| Jacob Cowing | 2 | 14 | 7.0 | 0 | 7 | 7 |
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| Luke Farrell | 1 | 13 | 13.0 | 0 | 13 | 2 |
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| Trenton Irwin | 2 | 11 | 5.5 | 0 | 7 | 4 |
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| Deebo Samuel Sr. | 1 | 4 | 4.0 | 0 | 4 | 2 |
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| Khalil Herbert | 1 | 0 | 0.0 | 0 | 0 | 1 |
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| Brayden Willis | 0 | 0 | 0.0 | 0 | 0 | 2 |
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| Will Pauling | 0 | 0 | 0.0 | 0 | 0 | 1 |
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| Fumbles | FUM | LOST | REC |
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| Adrian Martinez | 1 | 0 | 1 |
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| KhaDarel Hodge | 0 | 0 | 1 |
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| Defensive | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
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| Jalen Stroman | 6 | 5 | 0 | 0 | 0 | 0 | 0 |
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| Tatum Bethune | 6 | 3 | 0 | 2 | 0 | 0 | 0 |
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| Nick Martin | 5 | 4 | 0 | 0 | 0 | 0 | 0 |
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| Garret Wallow | 4 | 2 | 0 | 0 | 0 | 0 | 0 |
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| Jakob Robinson | 3 | 3 | 0 | 1 | 1 | 0 | 0 |
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| Ephesians Prysock | 3 | 1 | 0 | 0 | 1 | 0 | 0 |
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| Quinton Bell | 3 | 0 | 0 | 0 | 0 | 0 | 0 |
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| Renardo Green | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
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| Sam Okuayinonu | 2 | 2 | 0 | 1 | 0 | 0 | 0 |
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| Jaden Dugger | 2 | 2 | 0 | 0 | 1 | 0 | 0 |
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| Sincere McCormick | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Jordan Watkins | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
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| Victor Dimukeje | 1 | 1 | 1 | 1 | 0 | 1 | 0 |
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| Siran Neal | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Ashtyn Davis | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Jack Jones | 1 | 1 | 0 | 0 | 2 | 0 | 0 |
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| Khalil Herbert | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Deommodore Lenoir | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Bryson Eason | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
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| Romello Height | 1 | 1 | 0 | 1 | 0 | 0 | 0 |
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| Will Pauling | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Darrell Luter Jr. | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
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| Ji'Ayir Brown | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Larry Worth III | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Ogbo Okoronkwo | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
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| Brayden Willis | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
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| Patrick McMorris | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
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| James Thompson Jr. | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
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| Sebastian Valdez | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
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| KickReturns | NO | YDS | AVG | LONG | TD |
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| Jordan Watkins | 2 | 44 | 22.0 | 25 | 0 |
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| Khalil Herbert | 1 | 29 | 29.0 | 29 | 0 |
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| PuntReturns | NO | YDS | AVG | LONG | TD |
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| Jacob Cowing | 2 | 86 | 43.0 | 83 | 1 |
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| Will Pauling | 2 | 12 | 6.0 | 8 | 0 |
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| Kicking | FG | PCT | LONG | XP | PTS |
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| Eddy Pineiro | 2/2 | 100.0 | 48 | 5/5 | 11 |
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| Punting | NO | YDS | AVG | TB | In 20 | LONG |
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| Corliss Waitman | 5 | 245 | 49.0 | 1 | 0 | 55 |
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